The Playbook: Previewing Packers-49ers, Redskins-Eagles, other Week 1 games | Audibles – SI.com

New England at Buffalo (1 p.m. ET, CBS): Look for a no-huddle vs. no-huddle matchup here. The Patriots are on the vanguard of today’s speed offenses, and they’ll want to keep Buffalo’s multi-tiered defense in base nickel coverage. The Bills are starting rookie quarterback EJ Manuel, who will benefit from quicker action and timing passes to his targets. Running backs could be the key — Bill Belichick knows how dangerous C.J. Spiller is, and Pats back Shane Vereen can line up all along the formation. – DF